| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Will Smith | C | LAD | 30 | |
| Austin Wells | C | NYA | 25 | |
| Pete Alonso | 1B | NYN | 30 | |
| Willson Contreras | 1B | StL | 32 | |
| Colt Keith | 1B (2B) | Det | 23 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Jeff McNeil | 2B | NYN | 33 | |
| Gabriel Arias | SS (2B,3B) | Cle | 25 | |
| Bo Bichette | SS | Tor | 27 | |
| Elly De La Cruz | SS | Cin | 23 | |
| Jeremy Pena | SS | Hou | 27 | |
| Alex Bregman | 3B | Bos | 31 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Ronald Acuna Jr. | OF | Atl | 27 | March 25, 2025:10 Day IL |
| Jordan Beck | OF | Col | 24 | |
| JJ Bleday | OF | Oak | 27 | |
| Byron Buxton | OF | Min | 31 | |
| Jackson Chourio | OF | Mil | 21 | |
| Dylan Crews | OF | Was | 23 | |
| Sal Frelick | OF | Mil | 25 | |
| Jordan Walker | OF | StL | 22 | |
| Brayan Bello | SP | Bos | 25 | |
| Hunter Brown | SP | Hou | 26 | |
| Clay Holmes | SP | NYN | 32 | |
| Jackson Jobe | SP | Det | 22 | |
| Tyler Mahle | SP | Tex | 30 | |
| Dustin May | SP | LAD | 27 | |
| Casey Mize | SP | Det | 28 | |
| Mitchell Parker | SP | Was | 25 | |
| Ryan Helsley | RP | StL | 30 | |
| Luke Jackson | RP | Tex | 33 | |
| Mason Miller | RP | Oak | 26 |