| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Gabriel Moreno | C | Ari | 25 | |
| Cal Raleigh | C | Sea | 28 | |
| Jake Burger | 1B | Tex | 29 | |
| Andrew Vaughn | 1B | ChA | 27 | |
| Wilmer Flores | 2B | SF | 33 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Ketel Marte | 2B | Ari | 31 | |
| Willy Adames | SS | SF | 29 | |
| Geraldo Perdomo | SS | Ari | 25 | |
| Ryan McMahon | 3B | Col | 30 | |
| Jorge Polanco | 3B | Sea | 31 | |
| Jose Ramirez | 3B | Cle | 32 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Randy Arozarena | OF | Sea | 30 | |
| Heston Kjerstad | OF | Bal | 26 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Jorge Soler | OF | LAA | 32 | |
| Taylor Ward | OF | LAA | 31 | |
| Logan Allen | SP | Cle | 26 | |
| Luis Castillo | SP | Sea | 32 | |
| Sonny Gray | SP | StL | 35 | |
| Tanner Houck | SP | Bos | 28 | |
| Jake Irvin | SP | Was | 28 | |
| Merrill Kelly | SP | Ari | 36 | |
| Mike Lorenzen | SP | KC | 33 | |
| Ryan Pepiot | SP | TB | 27 | |
| Freddy Peralta | SP | Mil | 28 | |
| Eduardo Rodriguez | SP | Ari | 32 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Emmanuel Clase | RP | Cle | 27 | |
| Kyle Finnegan | RP | Was | 33 | |
| Devin Williams | RP | NYA | 30 |