| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ryan Jeffers | C | Min | 27 | |
| J.T. Realmuto | C | Phi | 34 | |
| Michael Busch | 1B | ChN | 27 | |
| Nolan Schanuel | 1B | LAA | 23 | |
| Christian Walker | 1B | Hou | 34 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Jonathan India | 2B (3B,OF) | KC | 28 | |
| Luis Rengifo | 2B (3B) | LAA | 28 | |
| J.P. Crawford | SS | Sea | 30 | |
| Xavier Edwards | SS | Mia | 25 | |
| Oswald Peraza | SS (3B) | NYA | 24 | |
| Matt Chapman | 3B | SF | 32 | |
| Connor Norby | 3B | Mia | 24 | |
| Matt Vierling | 3B | Det | 28 | March 27, 2025:10 Day IL |
| Brenton Doyle | OF | Col | 26 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Juan Soto | OF | NYN | 26 | |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Sandy Alcantara | SP | Mia | 29 | |
| Ronel Blanco | SP | Hou | 31 | |
| Kris Bubic | SP | KC | 27 | |
| Corbin Burnes | SP | Ari | 30 | |
| Bowden Francis | SP | Tor | 29 | |
| Grant Holmes | SP | Atl | N/A | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Luis Ortiz | SP | Cle | 26 | |
| Clarke Schmidt | SP | NYA | 29 | |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Zack Wheeler | SP | Phi | 34 | |
| Jhoan Duran | RP | Min | 27 | |
| Raisel Iglesias | RP | Atl | 35 |