| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Jeimer Candelario | 1B (3B) | Cin | 31 | April 30, 2025:10 Day IL |
| Willson Contreras | 1B | StL | 32 | |
| Vladimir Guerrero Jr. | 1B | Tor | 26 | |
| Carlos Santana | 1B | Cle | 39 | |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Ketel Marte | 2B | Ari | 31 | |
| Bryson Stott | 2B | Phi | 27 | |
| Francisco Lindor | SS | NYN | 31 | |
| Mark Vientos | 3B | NYN | 25 | |
| Byron Buxton | OF | Min | 31 | |
| Michael Conforto | OF | LAD | 32 | |
| Colton Cowser | OF | Bal | 25 | March 31, 2025:60 Day IL-Left thumb fracture |
| Ian Happ | OF | ChN | 30 | |
| Trevor Larnach | OF | Min | 28 | |
| Brandon Marsh | OF | Phi | 27 | April 20, 2025:10 Day IL |
| Heliot Ramos | OF | SF | 25 | |
| Bryan Reynolds | OF | Pit | 30 | |
| Lane Thomas | OF | Cle | 29 | April 22, 2025:10 Day IL |
| Jordan Walker | OF | StL | 22 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| James Wood | OF | Was | 22 | |
| Dylan Cease | SP | SD | 29 | |
| Clay Holmes | SP | NYN | 32 | |
| Yusei Kikuchi | SP | LAA | 33 | |
| Nick Lodolo | SP | Cin | 27 | |
| Reynaldo Lopez | SP | Atl | 31 | March 31, 2025:60 Day IL |
| Aaron Nola | SP | Phi | 31 | |
| Brandon Pfaadt | SP | Ari | 26 | |
| Ryan Weathers | SP | Mia | 25 | March 27, 2025:15 Day IL |
| Jeff Hoffman | RP | Tor | 32 |