| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| Carson Kelly | C | ChN | 30 | |
| Pedro Pages | C | StL | 26 | |
| Triston Casas | 1B | Bos | 25 | |
| Willson Contreras | 1B | StL | 32 | |
| Christian Encarnacion-Strand | 1B | Cin | 25 | April 17, 2025:10 Day IL |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Otto Lopez | 2B | Mia | 26 | |
| Zach McKinstry | 2B (3B,OF) | Det | 30 | |
| Matt McLain | 2B | Cin | 25 | |
| Bo Bichette | SS | Tor | 27 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Coby Mayo | 3B | Bal | 23 | |
| Connor Norby | 3B | Mia | 24 | |
| Cody Bellinger | OF | NYA | 29 | |
| Byron Buxton | OF | Min | 31 | |
| Evan Carter | OF | Tex | 22 | |
| Oneil Cruz | OF | Pit | 26 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Andrew Abbott | SP | Cin | 25 | |
| Taj Bradley | SP | TB | 24 | |
| Walker Buehler | SP | Bos | 30 | |
| Corbin Burnes | SP | Ari | 30 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Matthew Liberatore | SP | StL | 25 | |
| Tylor Megill | SP | NYN | 29 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Robbie Ray | SP | SF | 33 | |
| JP Sears | SP | Oak | 29 | |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Randy Vasquez | SP | SD | 26 |