| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Drake Baldwin | C | Atl | 24 | |
| Samuel Basallo | C | Bal | 20 | |
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| Carson Kelly | C | ChN | 30 | |
| Christian Encarnacion-Strand | 1B | Cin | 25 | April 17, 2025:10 Day IL |
| Bryce Harper | 1B | Phi | 32 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Matt McLain | 2B | Cin | 25 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Dansby Swanson | SS | ChN | 31 | |
| Jacob Wilson | SS | Oak | 23 | |
| Matt Chapman | 3B | SF | 32 | |
| Brady House | 3B | Was | 21 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Cody Bellinger | OF | NYA | 29 | |
| Kerry Carpenter | OF | Det | 27 | |
| Evan Carter | OF | Tex | 22 | |
| Jasson Dominguez | OF | NYA | 22 | |
| Michael Harris II | OF | Atl | 24 | |
| Chandler Simpson | OF | TB | 24 | |
| George Springer | OF | Tor | 35 | |
| Spencer Arrighetti | SP | Hou | N/A | April 08, 2025:15 Day IL |
| Jose Berrios | SP | Tor | 30 | |
| Nick Lodolo | SP | Cin | 27 | |
| Zebby Matthews | SP | Min | N/A | |
| Tylor Megill | SP | NYN | 29 | |
| Drew Rasmussen | SP | TB | 29 | |
| Robbie Ray | SP | SF | 33 | |
| José Soriano | SP | LAA | 26 | |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Randy Vasquez | SP | SD | 26 | |
| Camilo Doval | RP | SF | 27 | |
| Raisel Iglesias | RP | Atl | 35 |