| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Joey Bart | C | Pit | 28 | |
| Alejandro Kirk | C | Tor | 26 | |
| Matt Olson | 1B | Atl | 31 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Nolan Schanuel | 1B | LAA | 23 | |
| Gavin Lux | 2B (OF) | Cin | 27 | |
| Ketel Marte | 2B | Ari | 31 | |
| Gabriel Arias | SS (2B,3B) | Cle | 25 | |
| Xander Bogaerts | SS | SD | 32 | |
| Trevor Story | SS | Bos | 32 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Alec Bohm | 3B | Phi | 28 | |
| Noelvi Marte | 3B | Cin | 23 | |
| JJ Bleday | OF | Oak | 27 | |
| Nick Castellanos | OF | Phi | 33 | |
| Sal Frelick | OF | Mil | 25 | |
| Wyatt Langford | OF | Tex | 23 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Jordan Walker | OF | StL | 22 | |
| Brayan Bello | SP | Bos | 25 | |
| Corbin Burnes | SP | Ari | 30 | |
| Andrew Heaney | SP | Pit | 33 | |
| Tanner Houck | SP | Bos | 28 | |
| Mike Lorenzen | SP | KC | 33 | |
| Tyler Mahle | SP | Tex | 30 | |
| Casey Mize | SP | Det | 28 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| David Peterson | SP | NYN | 29 | |
| Tarik Skubal | SP | Det | 28 | |
| Luke Weaver | SP (RP) | NYA | 31 | |
| Josh Hader | RP | Hou | 31 | |
| Ryan Helsley | RP | StL | 30 |