| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Tyler Heineman | C | Tor | 33 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Nathaniel Lowe | 1B | Was | 29 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Eric Wagaman | 1B (OF) | Mia | N/A | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Ketel Marte | 2B | Ari | 31 | |
| Michael Massey | 2B | KC | 27 | |
| Mookie Betts | SS | LAD | 32 | |
| Trea Turner | SS | Phi | 31 | |
| Sebastian Walcott | SS | Tex | 19 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Jose Ramirez | 3B | Cle | 32 | |
| Randy Arozarena | OF | Sea | 30 | |
| Evan Carter | OF | Tex | 22 | |
| Trent Grisham | OF | NYA | 28 | |
| Ceddanne Rafaela | OF | Bos | 24 | |
| Victor Scott | OF | StL | 24 | |
| Jordan Walker | OF | StL | 22 | |
| Max Fried | SP | NYA | 31 | |
| Kevin Gausman | SP | Tor | 34 | |
| Logan Gilbert | SP | Sea | 27 | April 26, 2025:15 Day IL |
| Shota Imanaga | SP | ChN | 31 | |
| Max Scherzer | SP | Tor | 40 | March 30, 2025:15 Day IL-Thumb |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Luis Severino | SP | Oak | 31 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Justin Verlander | SP | SF | 42 | |
| Alexis Diaz | RP | Cin | 28 | |
| Camilo Doval | RP | SF | 27 | |
| Josh Hader | RP | Hou | 31 | |
| Mason Miller | RP | Oak | 26 |