| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Mejia | C | SD | 25 | |
| Pedro Severino | C (DH) | Bal | 27 | |
| Paul Goldschmidt | 1B (DH) | StL | 33 | |
| Dan Murphy | 1B (DH) | Col | 35 | |
| Carlos Santana | 1B | Cle | 34 | |
| Hanser Alberto | 2B (3B) | Bal | 28 | |
| Gavin Lux | 2B | LAD | 23 | |
| Didi Gregorius | SS | Phi | 30 | |
| Kevin Newman | SS (2B) | Pit | 27 | September 20, 2020:10 Day IL-Left knee contusion |
| Asdrubal Cabrera | 3B (1B,DH) | Was | 35 | |
| Anthony Rendon | 3B | LAA | 30 | |
| Corey Dickerson | OF (DH) | Mia | 31 | |
| Jasson Dominguez | OF | NYA | 17 | |
| Austin Hays | OF | Bal | 25 | |
| Max Kepler | OF | Min | 27 | |
| Wil Myers | OF | SD | 29 | |
| Gregory Polanco | OF (DH) | Pit | 29 | |
| Bryan Reynolds | OF | Pit | 25 | |
| Nelson Cruz | DH | Min | 40 | |
| Johnny Cueto | SP | SF | 34 | |
| Lucas Giolito | SP | ChA | 26 | |
| Tony Gonsolin | SP | LAD | 26 | |
| Jon Lester | SP | ChN | 36 | |
| Casey Mize | SP | Det | 23 | |
| Aaron Nola | SP | Phi | 27 | |
| James Paxton | SP | NYA | 32 | August 21, 2020:10 Day IL-Flexor strain, left forearm |
| Mike Soroka | SP | Atl | 23 | August 04, 2020:60 Day IL-Torn right Achilles - out for season |
| Forrest Whitley | SP | Hou | 23 | |
| Randy Dobnak | RP (SP) | Min | 25 | |
| Yoshihisa Hirano | RP | Sea | 36 | |
| Daniel Hudson | RP | Was | 33 | |
| Kenley Jansen | RP | LAD | 33 | |
| Taylor Williams | RP (SP) | SD | 29 |