| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Austin Wynns | C | Cin | 34 | |
| Yandy Diaz | 1B | TB | 33 | |
| Ty France | 1B | Min | 30 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| CJ Abrams | SS | Was | 24 | |
| J.P. Crawford | SS | Sea | 30 | |
| Geraldo Perdomo | SS | Ari | 25 | |
| Nolan Arenado | 3B | StL | 34 | |
| Matt Chapman | 3B | SF | 32 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Nick Castellanos | OF | Phi | 33 | |
| Steven Kwan | OF | Cle | 27 | |
| Trevor Larnach | OF | Min | 28 | |
| George Springer | OF | Tor | 35 | |
| Giancarlo Stanton | OF | NYA | 35 | March 26, 2025:60 Day IL |
| Mike Yastrzemski | OF | SF | 34 | |
| Tyler Anderson | SP | LAA | 35 | |
| Matt Boyd | SP | ChN | 34 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Jacob deGrom | SP | Tex | 36 | |
| Luis Gil | SP | NYA | 26 | March 24, 2025:60 Day IL |
| Andrew Heaney | SP | Pit | 33 | |
| Mike Lorenzen | SP | KC | 33 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Andre Pallante | SP | StL | 26 | |
| Mitchell Parker | SP | Was | 25 | |
| Freddy Peralta | SP | Mil | 28 | |
| Jose Quintana | SP | Mil | 36 | |
| Kyle Finnegan | RP | Was | 33 | |
| Kenley Jansen | RP | LAA | 37 |