| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Shea Langeliers | C | Oak | 27 | |
| Yohel Pozo | C | StL | 27 | |
| Connor Wong | C | Bos | 28 | |
| Pete Alonso | 1B | NYN | 30 | |
| Jac Caglianone | 1B | KC | 22 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Ben Rice | 1B | NYA | 26 | |
| Zach McKinstry | 2B (3B,OF) | Det | 30 | |
| Gleyber Torres | 2B | Det | 28 | |
| Enmanuel Valdez | 2B (1B) | Pit | 26 | |
| Willy Adames | SS | SF | 29 | |
| Dansby Swanson | SS | ChN | 31 | |
| Max Muncy | 3B | LAD | 34 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Miguel Vargas | 3B | ChA | 25 | |
| JJ Bleday | OF | Oak | 27 | |
| Jasson Dominguez | OF | NYA | 22 | |
| George Springer | OF | Tor | 35 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Shane Baz | SP | TB | 25 | |
| Ronel Blanco | SP | Hou | 31 | |
| Tony Gonsolin | SP | LAD | 30 | |
| Tanner Houck | SP | Bos | 28 | |
| Shota Imanaga | SP | ChN | 31 | |
| Jared Jones | SP | Pit | 23 | March 27, 2025:60 Day IL |
| Mitch Keller | SP | Pit | 29 | |
| Kumar Rocker | SP | Tex | N/A | April 25, 2025:15 Day IL |
| Roki Sasaki | SP | LAD | 23 | |
| Kodai Senga | SP | NYN | 32 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Jameson Taillon | SP | ChN | 33 | |
| Randy Vasquez | SP | SD | 26 | |
| Logan Webb | SP | SF | 28 |