| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Patrick Bailey | C | SF | 25 | |
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| J.T. Realmuto | C | Phi | 34 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Carlos Santana | 1B | Cle | 39 | |
| Luis Garcia | 2B | Was | 24 | |
| Nico Hoerner | 2B | ChN | 27 | |
| Mookie Betts | SS | LAD | 32 | |
| Gunnar Henderson | SS | Bal | 23 | |
| Geraldo Perdomo | SS | Ari | 25 | |
| Joey Ortiz | 3B (SS) | Mil | 26 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Nick Castellanos | OF | Phi | 33 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Bryan Reynolds | OF | Pit | 30 | |
| Victor Robles | OF | Sea | 27 | April 07, 2025:60 Day IL |
| Kyle Stowers | OF | Mia | 27 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Chris Bassitt | SP | Tor | 36 | |
| Edward Cabrera | SP | Mia | 27 | |
| Sonny Gray | SP | StL | 35 | |
| Hunter Greene | SP | Cin | 25 | |
| Gunnar Hoglund | SP | Oak | 25 | |
| Pablo Lopez | SP | Min | 29 | |
| Andre Pallante | SP | StL | 26 | |
| Robbie Ray | SP | SF | 33 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Justin Steele | SP | ChN | 29 | April 09, 2025:60 Day IL |
| Logan Webb | SP | SF | 28 | |
| Zack Wheeler | SP | Phi | 34 | |
| Trevor Williams | SP | Was | 33 | |
| Jordan Romano | RP | Phi | 32 |