| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Carson Kelly | C | ChN | 30 | |
| J.T. Realmuto | C | Phi | 34 | |
| Will Smith | C | LAD | 30 | |
| Willson Contreras | 1B | StL | 32 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Otto Lopez | 2B | Mia | 26 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Francisco Lindor | SS | NYN | 31 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Matt Chapman | 3B | SF | 32 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Jordan Westburg | 3B (2B) | Bal | 26 | April 28, 2025:10 Day IL |
| Jordan Beck | OF | Col | 24 | |
| JJ Bleday | OF | Oak | 27 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Jarren Duran | OF | Bos | 28 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| George Springer | OF | Tor | 35 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Andrew Abbott | SP | Cin | 25 | |
| Chris Bassitt | SP | Tor | 36 | |
| Brayan Bello | SP | Bos | 25 | |
| Jacob deGrom | SP | Tex | 36 | |
| Max Fried | SP | NYA | 31 | |
| Andrew Painter | SP | Phi | N/A | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Nick Pivetta | SP | SD | 32 | |
| Framber Valdez | SP | Hou | 31 | |
| Zack Wheeler | SP | Phi | 34 | |
| Aroldis Chapman | RP | Bos | 37 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Josh Hader | RP | Hou | 31 |