| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Logan O'Hoppe | C | LAA | 25 | |
| Keibert Ruiz | C | Was | 26 | |
| Jeimer Candelario | 1B (3B) | Cin | 31 | April 30, 2025:10 Day IL |
| Deyvison De Los Santos | 1B | Mia | 21 | |
| Bryce Harper | 1B | Phi | 32 | |
| Tyler Soderstrom | 1B (OF) | Oak | 23 | |
| Matt McLain | 2B | Cin | 25 | |
| Bryson Stott | 2B | Phi | 27 | |
| Jeremy Pena | SS | Hou | 27 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Brady House | 3B | Was | 21 | |
| Manny Machado | 3B | SD | 32 | |
| Connor Norby | 3B | Mia | 24 | |
| Cody Bellinger | OF | NYA | 29 | |
| Dylan Crews | OF | Was | 23 | |
| Kameron Misner | OF | TB | N/A | |
| Andy Pages | OF | LAD | 24 | |
| Chandler Simpson | OF | TB | 24 | |
| Juan Soto | OF | NYN | 26 | |
| Kyle Stowers | OF | Mia | 27 | |
| Osvaldo Bido | SP | Oak | N/A | |
| Taj Bradley | SP | TB | 24 | |
| Griffin Canning | SP | NYN | 28 | |
| Andrew Heaney | SP | Pit | 33 | |
| Matthew Liberatore | SP | StL | 25 | |
| Max Meyer | SP | Mia | 26 | |
| Aaron Nola | SP | Phi | 31 | |
| Chris Sale | SP | Atl | 36 | |
| Max Scherzer | SP | Tor | 40 | March 30, 2025:15 Day IL-Thumb |
| Clarke Schmidt | SP | NYA | 29 | |
| Luis Severino | SP | Oak | 31 | |
| Hayden Wesneski | SP | Hou | 27 | |
| Bryan Woo | SP | Sea | 25 |