| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Miguel Amaya | C | ChN | 26 | |
| William Contreras | C | Mil | 27 | |
| Colt Keith | 1B (2B) | Det | 23 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Zach Neto | SS | LAA | 24 | |
| Ezequiel Tovar | SS | Col | 23 | April 19, 2025:10 Day IL |
| Rafael Devers | 3B | Bos | 28 | |
| Jace Jung | 3B | Det | 24 | |
| Jorge Polanco | 3B | Sea | 31 | |
| Ben Williamson | 3B | Sea | N/A | |
| Teoscar Hernández | OF | LAD | 32 | |
| Aaron Judge | OF | NYA | 33 | |
| Brandon Nimmo | OF | NYN | 32 | |
| Lars Nootbaar | OF | StL | 27 | |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Alex Verdugo | OF | Atl | 28 | |
| Marcell Ozuna | DH | Atl | 34 | |
| Shane Baz | SP | TB | 25 | |
| Matt Boyd | SP | ChN | 34 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Nestor Cortes Jr. | SP | Mil | 30 | April 06, 2025:60 Day IL-Left elbow flexor strain |
| Hunter Dobbins | SP | Bos | N/A | |
| Hunter Greene | SP | Cin | 25 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Tyler Mahle | SP | Tex | 30 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Jose Quintana | SP | Mil | 36 | |
| Brady Singer | SP | Cin | 28 | |
| Justin Verlander | SP | SF | 42 | |
| Robert Suarez | RP | SD | 34 | |
| Ryan Walker | RP | SF | N/A |