| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Sean Murphy | C | Atl | 30 | |
| Keibert Ruiz | C | Was | 26 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Sebastian Walcott | SS | Tex | 19 | |
| Royce Lewis | 3B | Min | 25 | March 27, 2025:15 Day IL-Ab strain |
| Coby Mayo | 3B | Bal | 23 | |
| Cam Smith | 3B (OF) | Hou | 22 | |
| Jordan Westburg | 3B (2B) | Bal | 26 | April 28, 2025:10 Day IL |
| Lawrence Butler | OF | Oak | 24 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Walker Jenkins | OF | Min | 20 | |
| Aaron Judge | OF | NYA | 33 | |
| Wyatt Langford | OF | Tex | 23 | |
| Julio Rodriguez | OF | Sea | 24 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Jordan Walker | OF | StL | 22 | |
| Taj Bradley | SP | TB | 24 | |
| Luis Gil | SP | NYA | 26 | March 24, 2025:60 Day IL |
| Sonny Gray | SP | StL | 35 | |
| Clay Holmes | SP | NYN | 32 | |
| Reese Olson | SP | Det | 25 | |
| Andrew Painter | SP | Phi | N/A | |
| Drew Rasmussen | SP | TB | 29 | |
| Robbie Ray | SP | SF | 33 | |
| Gavin Williams | SP | Cle | 25 | |
| Aroldis Chapman | RP | Bos | 37 | |
| Jeff Hoffman | RP | Tor | 32 | |
| Trevor Megill | RP | Mil | 31 |