| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Jonah Heim | C | Tex | 29 | |
| Edgar Quero | C | ChA | 22 | |
| Will Smith | C | LAD | 30 | |
| Pete Alonso | 1B | NYN | 30 | |
| Matt Mervis | 1B | Mia | 27 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Ketel Marte | 2B | Ari | 31 | April 05, 2025:10 Day IL |
| Willy Adames | SS | SF | 29 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Jacob Wilson | SS | Oak | 23 | |
| Royce Lewis | 3B | Min | 25 | March 27, 2025:15 Day IL-Ab strain |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Miguel Vargas | 3B | ChA | 25 | |
| Evan Carter | OF | Tex | 22 | |
| Max Clark | OF | Det | 20 | |
| Austin Hays | OF | Cin | 29 | |
| Steven Kwan | OF | Cle | 27 | |
| Andy Pages | OF | LAD | 24 | |
| Chandler Simpson | OF | TB | 24 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Taylor Ward | OF | LAA | 31 | |
| Andrew Abbott | SP | Cin | 25 | |
| Walker Buehler | SP | Bos | 30 | |
| Logan Gilbert | SP | Sea | 27 | April 26, 2025:15 Day IL |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Nick Lodolo | SP | Cin | 27 | |
| Zebby Matthews | SP | Min | N/A | |
| Tylor Megill | SP | NYN | 29 | |
| Jeffrey Springs | SP | Oak | 32 | |
| Randy Vasquez | SP | SD | 26 | |
| Zack Wheeler | SP | Phi | 34 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Ryan Helsley | RP | StL | 30 |