| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Miguel Amaya | C | ChN | 26 | |
| Yainer Diaz | C | Hou | 26 | |
| Dillon Dingler | C | Det | N/A | |
| Tyler Heineman | C | Tor | 33 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Spencer Torkelson | 1B | Det | 25 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Luis Rengifo | 2B (3B) | LAA | 28 | |
| CJ Abrams | SS | Was | 24 | |
| J.P. Crawford | SS | Sea | 30 | |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Mark Vientos | 3B | NYN | 25 | |
| Jackson Chourio | OF | Mil | 21 | |
| Charlie Condon | OF | Col | 22 | |
| Brenton Doyle | OF | Col | 26 | |
| Jarren Duran | OF | Bos | 28 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Kameron Misner | OF | TB | N/A | |
| Victor Robles | OF | Sea | 27 | April 07, 2025:60 Day IL |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Sandy Alcantara | SP | Mia | 29 | |
| Jose Berrios | SP | Tor | 30 | |
| Corbin Burnes | SP | Ari | 30 | |
| Jack Flaherty | SP | Det | 29 | |
| David Peterson | SP | NYN | 29 | |
| Nick Pivetta | SP | SD | 32 | |
| Paul Skenes | SP | Pit | 22 | |
| Jeffrey Springs | SP | Oak | 32 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Jameson Taillon | SP | ChN | 33 | |
| Zack Wheeler | SP | Phi | 34 | |
| Carlos Estevez | RP | KC | 32 | |
| Justin Martinez | RP | Ari | 23 | May 01, 2025:15 Day IL |