| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Joey Bart | C | Pit | 28 | |
| Ryan Jeffers | C | Min | 27 | |
| Pete Alonso | 1B | NYN | 30 | |
| Luis Arraez | 1B | SD | 28 | |
| Rowdy Tellez | 1B | Sea | 30 | |
| Otto Lopez | 2B | Mia | 26 | |
| Matt McLain | 2B | Cin | 25 | |
| Gleyber Torres | 2B | Det | 28 | |
| Trevor Story | SS | Bos | 32 | |
| Anthony Volpe | SS | NYA | 24 | |
| Isaac Paredes | 3B | Hou | 26 | |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Oneil Cruz | OF | Pit | 26 | |
| Jarren Duran | OF | Bos | 28 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Riley Greene | OF | Det | 24 | |
| Lars Nootbaar | OF | StL | 27 | |
| Jorge Soler | OF | LAA | 32 | |
| Hayden Birdsong | SP (RP) | SF | N/A | |
| Jack Flaherty | SP | Det | 29 | |
| Mike Lorenzen | SP | KC | 33 | |
| Bailey Ober | SP | Min | 29 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| Roki Sasaki | SP | LAD | 23 | |
| JP Sears | SP | Oak | 29 | |
| Brady Singer | SP | Cin | 28 | |
| Paul Skenes | SP | Pit | 22 | |
| Tarik Skubal | SP | Det | 28 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Justin Verlander | SP | SF | 42 | |
| Zack Wheeler | SP | Phi | 34 |