| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Yainer Diaz | C | Hou | 26 | |
| Alejandro Kirk | C | Tor | 26 | |
| Michael Busch | 1B | ChN | 27 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Matt Olson | 1B | Atl | 31 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Brice Turang | 2B | Mil | 25 | |
| Mookie Betts | SS | LAD | 32 | |
| Jose Caballero | SS (3B,OF) | TB | 28 | |
| Trea Turner | SS | Phi | 31 | |
| Jacob Wilson | SS | Oak | 23 | |
| Max Muncy | 3B | LAD | 34 | |
| Alec Burleson | OF (1B) | StL | 26 | |
| Evan Carter | OF | Tex | 22 | |
| Nick Castellanos | OF | Phi | 33 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Walker Jenkins | OF | Min | 20 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Taylor Ward | OF | LAA | 31 | |
| Andrew Abbott | SP | Cin | 25 | |
| Shane Baz | SP | TB | 25 | |
| Garrett Crochet | SP | Bos | 25 | |
| Tyler Glasnow | SP | LAD | 31 | April 29, 2025:15 Day IL |
| Logan Henderson | SP | Mil | N/A | |
| Clay Holmes | SP | NYN | 32 | |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Randy Vasquez | SP | SD | 26 | |
| Zack Wheeler | SP | Phi | 34 | |
| Alexis Diaz | RP | Cin | 28 | |
| Carlos Estevez | RP | KC | 32 | |
| Tanner Scott | RP | LAD | 30 |