| Position | Starters | Team | Opponents |
| C (1B,C) | Salvador Perez | KC | ChA(4) Bos(3) |
| 1B | Christian Walker | Hou | @Mil(3) Cin(3) |
| 2B (SS,OF) | Brendan Donovan | StL | Pit(3) @Was(3) |
| SS | Trea Turner | Phi | @TB(3) @Cle(3) |
| 3B | Manny Machado | SD | @NYA(3) @Col(3) |
| OF | Brandon Nimmo | NYN | @Ari(3) ChN(3) |
| OF | Lars Nootbaar | StL | Pit(3) @Was(3) |
| OF | Taylor Ward | LAA | Tor(3) Bal(3) |
| DH | Mookie Betts | LAD | @Mia(3) @Ari(4) |
| Position | 1st Backup | Team | Opponents |
| C | Miguel Amaya | ChN | SF(3) @NYN(3) |
| 1B | Nolan Schanuel | LAA | Tor(3) Bal(3) |
| 2B | Jake Cronenworth | SD | @NYA(3) @Col(3) |
| 3B | Ernie Clement | Tor | @LAA(3) @Sea(3) |
| OF | Andrew Benintendi | ChA | @KC(4) Mia(3) |
| DH (1B,OF) | Spencer Steer | Cin | @Atl(4) @Hou(3) |
| Position | 2nd Backup | Team | Opponents |
| DH | Victor Robles | Sea | @Oak(3) Tor(3) |
| Position | 3rd Backup | Team | Opponents |
| OF | Tyler O'Neill | Bal | @Min(3) @LAA(3) |
| Position | Bench | Team | Opponents |
| SS (3B) | Oswaldo Cabrera | NYA | SD(3) @Oak(3) |
| Pitching Staff Alignment |
| 10 Starts, 0 Relievers |
| Position | Pitching Order | Team | Opponents | Next Scheduled Start(s) |
| 1st SP | Bryce Miller | Sea | @Oak(3) Tor(3) | This Monday at Oak (Luis Severino) |
| 2nd SP | Nick Martinez | Cin | @Atl(4) @Hou(3) | This Friday at Hou (Framber Valdez) |
| 3rd SP | Brady Singer | Cin | @Atl(4) @Hou(3) | This Monday at Atl (AJ Smith-Shawver) |
| 4th SP | Pablo Lopez | Min | Bal(3) SF(3) | This Tuesday vs Bal (Cade Povich) |
| 5th SP | Tyler Anderson | LAA | Tor(3) Bal(3) | This Tuesday vs Tor (TBD) |
| 6th SP | Mitchell Parker | Was | Cle(3) StL(3) | This Wednesday vs Cle (Logan Allen) |
| 7th SP | Jameson Taillon | ChN | SF(3) @NYN(3) | This Friday at NYN (Clay Holmes) |
| 8th SP | Matthew Liberatore | StL | Pit(3) @Was(3) | This Tuesday vs Pit (Paul Skenes) |
| 9th SP | Jose Quintana | Mil | Hou(3) @TB(3) | This Friday at TB (Zack Littell) |
| 10th SP | Jordan Hicks | SF | @ChN(3) @Min(3) | This Friday at Min (Bailey Ober) |
| 11th SP | Kutter Crawford | Bos | Tex(3) @KC(3) | Has Not Played Yet |
| 12th SP | Shane Bieber | Cle | @Was(3) Phi(3) | Has Not Played Yet |
| 13th SP | Gavin Stone | LAD | @Mia(3) @Ari(4) | Has Not Played Yet |
| Position | Injured List | Team | Opponents |
| OF | Ronald Acuna Jr. | Atl | Cin(4) @Pit(3) |
| SP | Aaron Civale | Mil | Hou(3) @TB(3) |
| SP | Ranger Suarez | Phi | @TB(3) @Cle(3) |