| Position | Starters | Team | Opponents |
| C | Logan O'Hoppe | LAA | Tor(3) Bal(3) |
| 1B (OF) | Pavin Smith | Ari | NYN(3) LAD(4) |
| 2B (OF) | Tim Tawa | Ari | NYN(3) LAD(4) |
| SS | Anthony Volpe | NYA | SD(3) @Oak(3) |
| 3B | Austin Riley | Atl | Cin(4) @Pit(3) |
| OF | Byron Buxton | Min | Bal(3) SF(3) |
| OF | TJ Friedl | Cin | @Atl(4) @Hou(3) |
| OF | Cedric Mullins II | Bal | @Min(3) @LAA(3) |
| DH | Jonathan Aranda | TB | Phi(3) Mil(3) |
| Position | 1st Backup | Team | Opponents |
| C | Joey Bart | Pit | @StL(3) Atl(3) |
| 1B | Paul Goldschmidt | NYA | SD(3) @Oak(3) |
| 2B (3B,OF) | Jonathan India | KC | ChA(4) Bos(3) |
| 3B | Connor Norby | Mia | LAD(3) @ChA(3) |
| OF | Heliot Ramos | SF | @ChN(3) @Min(3) |
| DH | Kyle Stowers | Mia | LAD(3) @ChA(3) |
| Position | 2nd Backup | Team | Opponents |
| DH | Yandy Diaz | TB | Phi(3) Mil(3) |
| Position | Bench | Team | Opponents |
| 3B | Matt Shaw | ChN | SF(3) @NYN(3) |
| OF | Evan Carter | Tex | @Bos(3) @Det(3) |
| OF | Tyler O'Neill | Bal | @Min(3) @LAA(3) |
| OF | Andy Pages | LAD | @Mia(3) @Ari(4) |
| Pitching Staff Alignment |
| 7 Starts, 2 Relievers |
| Position | Pitching Order | Team | Opponents | Next Scheduled Start(s) |
| 1st SP | Taj Bradley | TB | Phi(3) Mil(3) | This Saturday vs Mil (Freddy Peralta) |
| 2nd SP | Hunter Brown | Hou | @Mil(3) Cin(3) | Last Pitched Saturday May 3rd |
| 3rd SP | Corbin Burnes | Ari | NYN(3) LAD(4) | This Saturday vs LAD (Dustin May) |
| 4th SP | Bryan Woo | Sea | @Oak(3) Tor(3) | This Wednesday at Oak (Gunnar Hoglund) |
| 5th SP | Max Meyer | Mia | LAD(3) @ChA(3) | This Friday at ChA (Bryse Wilson) |
| 6th SP | Matthew Liberatore | StL | Pit(3) @Was(3) | This Tuesday vs Pit (Paul Skenes) |
| 7th SP | Tanner Houck | Bos | Tex(3) @KC(3) | This Thursday vs Tex (Jack Leiter) |
| 8th SP | Chase Dollander | Col | Det(3) SD(3) | This Tuesday vs Det (Jackson Jobe) |
| 1st RP | Edwin Diaz | NYN | @Ari(3) ChN(3) | Last Pitched Saturday April 26th |
| 2nd RP | Kenley Jansen | LAA | Tor(3) Bal(3) | Last Pitched Saturday May 3rd |
| 3rd RP | Tanner Scott | LAD | @Mia(3) @Ari(4) | Last Pitched Friday May 2nd |
| Position | Injured List | Team | Opponents |
| 1B | Christian Encarnacion-Strand | Cin | @Atl(4) @Hou(3) |
| 2B | Jake Cronenworth | SD | @NYA(3) @Col(3) |
| SP | Blake Snell | LAD | @Mia(3) @Ari(4) |