| Position | Starters | Team | Opponents |
| C | William Contreras | Mil | Hou(3) @TB(3) |
| 1B | Spencer Torkelson | Det | @Col(3) Tex(3) |
| 2B (SS,OF) | Brendan Donovan | StL | Pit(3) @Was(3) |
| SS | Mookie Betts | LAD | @Mia(3) @Ari(4) |
| 3B | Matt Chapman | SF | @ChN(3) @Min(3) |
| OF | Wilyer Abreu | Bos | Tex(3) @KC(3) |
| OF | Ian Happ | ChN | SF(3) @NYN(3) |
| OF | Teoscar Hernández | LAD | @Mia(3) @Ari(4) |
| DH | Freddie Freeman | LAD | @Mia(3) @Ari(4) |
| Position | 1st Backup | Team | Opponents |
| C | Bo Naylor | Cle | @Was(3) Phi(3) |
| 1B | Rhys Hoskins | Mil | Hou(3) @TB(3) |
| 2B | Jeff McNeil | NYN | @Ari(3) ChN(3) |
| SS | CJ Abrams | Was | Cle(3) StL(3) |
| 3B | Manny Machado | SD | @NYA(3) @Col(3) |
| OF | Trent Grisham | NYA | SD(3) @Oak(3) |
| DH | Nolan Arenado | StL | Pit(3) @Was(3) |
| Position | 2nd Backup | Team | Opponents |
| 2B | Wilmer Flores | SF | @ChN(3) @Min(3) |
| SS | Trevor Story | Bos | Tex(3) @KC(3) |
| OF | Brandon Nimmo | NYN | @Ari(3) ChN(3) |
| Position | 3rd Backup | Team | Opponents |
| OF (2B) | Tommy Edman | LAD | @Mia(3) @Ari(4) |
| Pitching Staff Alignment |
| 7 Starts, 2 Relievers |
| Position | Pitching Order | Team | Opponents | Next Scheduled Start(s) |
| 1st SP | Max Fried | NYA | SD(3) @Oak(3) | This Friday at Oak (Osvaldo Bido) |
| 2nd SP | Kevin Gausman | Tor | @LAA(3) @Sea(3) | This Friday at Sea (Luis Castillo) |
| 3rd SP | Jack Flaherty | Det | @Col(3) Tex(3) | This Friday vs Tex (Pat Corbin) |
| 4th SP | Andrew Heaney | Pit | @StL(3) Atl(3) | This Saturday vs Atl (AJ Smith-Shawver) |
| 5th SP | Ranger Suarez | Phi | @TB(3) @Cle(3) | This Saturday at Cle (Tanner Bibee) |
| 6th SP | Luis Severino | Oak | Sea(3) NYA(3) | This Monday vs Sea (Bryce Miller) |
| 7th SP | Jack Leiter | Tex | @Bos(3) @Det(3) | This Thursday at Bos (Tanner Houck) |
| 8th SP | Clarke Schmidt | NYA | SD(3) @Oak(3) | This Tuesday vs SD (Michael King) |
| 1st RP | José Alvarado | Phi | @TB(3) @Cle(3) | Last Pitched Friday May 2nd |
| 2nd RP | Camilo Doval | SF | @ChN(3) @Min(3) | Last Pitched Saturday May 3rd |
| 3rd RP | Luke Jackson | Tex | @Bos(3) @Det(3) | Last Pitched Wednesday April 30th |
| Position | Injured List | Team | Opponents |
| SP | Walker Buehler | Bos | Tex(3) @KC(3) |
| 2B | Tyler Fitzgerald | SF | @ChN(3) @Min(3) |
| SP | Logan Gilbert | Sea | @Oak(3) Tor(3) |