| Position | Starters | Team | Opponents |
| C | Sean Murphy | Atl | Cin(4) @Pit(3) |
| 1B | Christian Walker | Hou | @Mil(3) Cin(3) |
| SS | Gunnar Henderson | Bal | @Min(3) @LAA(3) |
| 3B | Ben Williamson | Sea | @Oak(3) Tor(3) |
| OF | Jackson Chourio | Mil | Hou(3) @TB(3) |
| OF | Kyle Schwarber | Phi | @TB(3) @Cle(3) |
| DH | Ozzie Albies | Atl | Cin(4) @Pit(3) |
| Position | 1st Backup | Team | Opponents |
| C | Austin Wells | NYA | SD(3) @Oak(3) |
| 2B | Luisangel Acuna | NYN | @Ari(3) ChN(3) |
| SS (2B,OF) | Kyren Paris | LAA | Tor(3) Bal(3) |
| 3B | Ke'Bryan Hayes | Pit | @StL(3) Atl(3) |
| OF | Cody Bellinger | NYA | SD(3) @Oak(3) |
| DH | Brenton Doyle | Col | Det(3) SD(3) |
| Position | 2nd Backup | Team | Opponents |
| OF | Christopher Morel | TB | Phi(3) Mil(3) |
| DH | Taylor Ward | LAA | Tor(3) Bal(3) |
| Position | Bench | Team | Opponents |
| 3B (2B,SS) | Chase Meidroth | ChA | @KC(4) Mia(3) |
| Pitching Staff Alignment |
| 7 Starts, 2 Relievers |
| Position | Pitching Order | Team | Opponents | Next Scheduled Start(s) |
| 1st SP | Logan Webb | SF | @ChN(3) @Min(3) | This Saturday at Min (Chris Paddack) |
| 2nd SP | Nathan Eovaldi | Tex | @Bos(3) @Det(3) | This Tuesday at Bos (Sean Newcomb) |
| 3rd SP | Seth Lugo | KC | ChA(4) Bos(3) | This Tuesday vs ChA (Sean Burke) |
| 4th SP | Freddy Peralta | Mil | Hou(3) @TB(3) | This Saturday at TB (Taj Bradley) |
| 5th SP | Ronel Blanco | Hou | @Mil(3) Cin(3) | This Monday at Mil (Tobias Myers) |
| 6th SP | Jose Quintana | Mil | Hou(3) @TB(3) | This Friday at TB (Zack Littell) |
| 7th SP | Brady Singer | Cin | @Atl(4) @Hou(3) | This Monday at Atl (AJ Smith-Shawver) |
| 8th SP | Mitchell Parker | Was | Cle(3) StL(3) | This Wednesday vs Cle (Logan Allen) |
| 9th SP | Tyler Anderson | LAA | Tor(3) Bal(3) | This Tuesday vs Tor (TBD) |
| 10th SP | JP Sears | Oak | Sea(3) NYA(3) | This Saturday vs NYA (Will Warren) |
| 11th SP | Jake Irvin | Was | Cle(3) StL(3) | This Monday vs Cle (Luis Ortiz) |
| 1st RP | Jhoan Duran | Min | Bal(3) SF(3) | Last Pitched Saturday May 3rd |
| 2nd RP | Robert Suarez | SD | @NYA(3) @Col(3) | Last Pitched Saturday May 3rd |
| Position | Injured List | Team | Opponents |
| 1B (3B) | Jeimer Candelario | Cin | @Atl(4) @Hou(3) |
| 2B | Jazz Chisholm Jr. | NYA | SD(3) @Oak(3) |
| OF | Austin Hays | Cin | @Atl(4) @Hou(3) |