| Rank | Score | Team | Week | Owner(s) |
| 1. | 438 | The Hokies | Week 5, 2000 | Scott Liskey |
| 2. | 429 | The Hokies | Week 14, 2000 | Scott Liskey |
| 3. | 374 | The Hokies | Week 3, 2000 | Scott Liskey |
| 4. | 367 | The Hokies | Week 17, 2000 | Scott Liskey |
| 5. | 362 | The Hokies | Week 19, 2000 | Scott Liskey |
| 6. | 353 | The Hokies | Week 2, 2000 | Scott Liskey |
| 7. | 346 | The Hokies | Week 8, 2000 | Scott Liskey |
| 8. | 341 | The Hokies | Week 16, 2000 | Scott Liskey |
| 9. | 339 | The Hokies | Week 11, 2000 | Scott Liskey |
| 10. | 335 | The Hokies | Week 12, 2000 | Scott Liskey |
| 11. | 330 | The Hokies | Week 18, 2000 | Scott Liskey |
| 12. | 313 | The Hokies | Week 10, 2000 | Scott Liskey |
| 13. | 308 | The Hokies | Week 1, 2000 | Scott Liskey |
| 14. | 303 | The Hokies | Week 13, 2000 | Scott Liskey |
| 15. | 298 | The Hokies | Week 9, 2000 | Scott Liskey |
| 16. | 294 | The Hokies | Week 6, 2000 | Scott Liskey |
| 17. | 279 | The Hokies | Week 4, 2000 | Scott Liskey |
| 18. | 269 | The Hokies | Week 7, 2000 | Scott Liskey |