| Round | Overall | Player |
|---|---|---|
| 1 | 10th | OF Matt Kemp LAD |
| 2 | 15th | 3B Evan Longoria TB |
| 3 | 34th | SP Justin Verlander Det |
| 4 | 39th | OF Curtis Granderson NYA |
| 5 | 58th | SP Josh Beckett Bos |
| 6 | 63rd | SS Jose Reyes NYN |
| 7 | 82nd | 2B Gordon Beckham ChA |
| 8 | 87th | RP Joakim Soria KC |
| 9 | 106th | OF Melvin Upton TB |
| 10 | 111th | SP A.J. Burnett NYA |
| 11 | 130th | SP Brett Anderson Oak |
| 12 | 135th | 1B Chris Davis Tex |
| 13 | 154th | SP Gavin Floyd ChA |
| 14 | 159th | RP Mike Gonzalez Bal |
| 15 | 178th | SP Francisco Liriano Min |
| 16 | 183rd | SP Jason Frasor Tor |
| 17 | 202nd | SS Rafael Furcal LAD |
| 18 | 207th | C Chris Iannetta Col |
| 19 | 226th | OF Julio Borbon Tex |
| 20 | 231st | OF Kyle Blanks SD |
| 21 | 250th | C Ben Molina Tex |
| 22 | 255th | SP Bud Norris Hou |
| 23 | 274th | 2B Orlando Hudson Min |
| 24 | 279th | OF Conor Jackson Oak |
| 25 | 298th | SP Ryan Madson Phi |
| 26 | 303rd | SP Ian Kennedy Ari |