| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | SS Hanley Ramirez Fla |
| 2 | 23rd | SP Zack Greinke Mil |
| 3 | 26th | 1B Adrian Gonzalez Bos |
| 4 | 47th | OF Carl Crawford Bos |
| 5 | 50th | 2B Aaron Hill Tor |
| 6 | 71st | OF Carlos Lee Hou |
| 7 | 74th | 3B Aramis Ramirez ChN |
| 8 | 95th | OF Shane Victorino Phi |
| 9 | 98th | SP Roy Oswalt Phi |
| 10 | 119th | RP Andrew Bailey Oak |
| 11 | 122nd | DH Mike Young Tex |
| 12 | 143rd | SP Ryan Dempster ChN |
| 13 | 146th | RP Billy Wagner Atl |
| 14 | 167th | OF Alexis Rios ChA |
| 15 | 170th | SP Joe Blanton Phi |
| 16 | 191st | SP Daisuke Matsuzaka Bos |
| 17 | 194th | SP Ervin Santana LAA |
| 18 | 215th | SP Jonathan Sanchez SF |
| 19 | 218th | OF Magglio Ordonez Det |
| 20 | 239th | SP Roberto Hernandez Cle |
| 21 | 242nd | SP Tim Wakefield Bos |
| 22 | 263rd | C A.J. Pierzynski ChA |
| 23 | 266th | 3B Miguel Tejada SD |
| 24 | 287th | 1B Aubrey Huff SF |
| 25 | 290th | SS J.J. Hardy Bal |
| 26 | 311th | OF Jeff Francoeur Tex |