| Round | Overall | Player |
|---|---|---|
| 1 | 11th | 1B Miguel Cabrera Det |
| 2 | 14th | SP Tim Lincecum SF |
| 3 | 35th | SP Jon Lester Bos |
| 4 | 38th | OF Andre Ethier LAD |
| 5 | 59th | RP Mariano Rivera NYA |
| 6 | 62nd | OF Ichiro Suzuki Sea |
| 7 | 83rd | 2B Dan Uggla Atl |
| 8 | 86th | SP Jake Peavy ChA |
| 9 | 107th | OF Bobby Abreu LAA |
| 10 | 110th | RP Jose Valverde Det |
| 11 | 131st | SS Elvis Andrus Tex |
| 12 | 134th | SP John Danks ChA |
| 13 | 155th | 3B Adrian Beltre Tex |
| 14 | 158th | SP Jorge de la Rosa Col |
| 15 | 179th | SP Rick Porcello Det |
| 16 | 182nd | DH Jason Kubel Min |
| 17 | 203rd | RP Matt Capps Min |
| 18 | 206th | OF Michael Bourn Hou |
| 19 | 227th | SP Erik Bedard Sea |
| 20 | 230th | SS Erick Aybar LAA |
| 21 | 251st | C Yadier Molina StL |
| 22 | 254th | OF Dexter Fowler Col |
| 23 | 275th | SP Jeremy Bonderman Det |
| 24 | 278th | RP Jon Rauch Min |
| 25 | 299th | 3B Kevin Kouzmanoff Oak |
| 26 | 302nd | SP Kevin Correia Pit |