| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | 1B Albert Pujols LAA |
| 2 | 23rd | C Joe Mauer Min |
| 3 | 26th | SP Cliff Lee Phi |
| 4 | 47th | SP Josh Johnson Fla |
| 5 | 50th | SP Clayton Kershaw LAD |
| 6 | 71st | OF Andre Ethier LAD |
| 7 | 74th | 2B Brandon Phillips Cin |
| 8 | 95th | OF Nick Markakis Bal |
| 9 | 98th | 3B Martin Prado Atl |
| 10 | 119th | DH Kendrys Morales LAA |
| 11 | 122nd | OF Shane Victorino Phi |
| 12 | 143rd | RP Jonathan Broxton LAD |
| 13 | 146th | SP Colby Lewis Tex |
| 14 | 167th | SS Rafael Furcal STL |
| 15 | 170th | 2B Gordon Beckham ChA |
| 16 | 191st | RP Chris Perez Cle |
| 17 | 194th | OF Michael Cuddyer Col |
| 18 | 215th | OF Brett Gardner NYA |
| 19 | 218th | SP Mark Buehrle Fla |
| 20 | 239th | SP Barry Zito SF |
| 21 | 242nd | 3B Mike Moustakas KC |
| 22 | 263rd | 1B Kila Ka'Aihue Oak |
| 23 | 266th | C Jarrod Saltalamacchia Bos |
| 24 | 287th | 3B Mike Aviles Bos |
| 25 | 290th | SP Jeff Niemann TB |
| 26 | 311th | DH Jim Thome Phi |
| 27 | 314th | C Jason Varitek Bos |
| 28 | 335th | SP Luke Hochevar KC |
| 29 | 338th | SP Bartolo Colon Oak |