| Round | Overall | Player |
|---|---|---|
| 1 | 5th | 1B Miguel Cabrera Det |
| 2 | 20th | 2B Dustin Pedroia Bos |
| 3 | 29th | 3B Ryan Zimmerman Was |
| 4 | 44th | SP David Price TB |
| 5 | 53rd | SP Matt Cain SF |
| 6 | 68th | SP Jered Weaver LAA |
| 7 | 77th | SP Dan Haren LAA |
| 8 | 92nd | SP Chad Billingsley LAD |
| 9 | 101st | RP Jon Papelbon Phi |
| 10 | 116th | RP Brian Wilson SF |
| 11 | 125th | OF Melvin Upton TB |
| 12 | 140th | OF Carlos Quentin SD |
| 13 | 149th | OF Bobby Abreu LAA |
| 14 | 164th | OF Adam Jones Bal |
| 15 | 173rd | SP Jair Jurrjens Atl |
| 16 | 188th | RP Chris Perez Cle |
| 17 | 197th | SP Jhoulys Chacin Col |
| 18 | 212th | OF Raul Ibanez Phi |
| 19 | 221st | 3B Ian Stewart ChN |
| 20 | 236th | SS J.J. Hardy Bal |
| 21 | 245th | OF Luke Scott TB |
| 22 | 260th | 1B Justin Smoak Sea |
| 23 | 269th | SS Jed Lowrie Hou |
| 24 | 284th | 1B Brett Wallace Hou |
| 25 | 293rd | SS Erick Aybar LAA |
| 26 | 308th | SP Chris Young NYN |
| 27 | 317th | C Nick Hundley SD |
| 28 | 332nd | C Miguel Olivo Sea |
| 29 | 341st | SP Bud Norris Hou |