| Round | Overall | Player |
|---|---|---|
| 1 | 5th | 3B Alex Rodriguez NYA |
| 2 | 20th | DH Adam Dunn ChA |
| 3 | 29th | SP Cliff Lee Phi |
| 4 | 44th | SP David Price TB |
| 5 | 53rd | C Brian McCann Atl |
| 6 | 68th | SP Zack Greinke Mil |
| 7 | 77th | OF Curtis Granderson NYA |
| 8 | 92nd | OF Colby Rasmus Tor |
| 9 | 101st | 2B Kelly Johnson Tor |
| 10 | 116th | SP Philip Hughes NYA |
| 11 | 125th | OF Drew Stubbs Cin |
| 12 | 140th | SP Jordan Zimmermann Was |
| 13 | 149th | OF Manny Ramirez TB |
| 14 | 164th | RP John Axford Mil |
| 15 | 173rd | RP Matt Thornton ChA |
| 16 | 188th | OF Angel Pagan SF |
| 17 | 197th | SP Jhoulys Chacin Col |
| 18 | 212th | C Chris Iannetta LAA |
| 19 | 221st | SS Jhonny Peralta Det |
| 20 | 236th | RP Brandon Lyon Hou |
| 21 | 245th | SP Wade Davis TB |
| 22 | 260th | SP Ivan Nova NYA |
| 23 | 269th | 1B Daric Barton Oak |
| 24 | 284th | 3B Placido Polanco Phi |
| 25 | 293rd | OF Alex Gordon KC |
| 26 | 308th | SP Daisuke Matsuzaka Bos |
| 27 | 317th | SP Jeff Niemann TB |
| 28 | 332nd | 2B Bill Hall SF |
| 29 | 341st | SS Yuniesky Betancourt KC |