| Round | Overall | Player |
|---|---|---|
| 1 | 4th | SS Troy Tulowitzki Col |
| 2 | 21st | OF Andrew McCutchen Pit |
| 3 | 28th | 1B Eric Hosmer KC |
| 4 | 45th | OF Nelson Cruz Tex |
| 5 | 52nd | 2B Ben Zobrist TB |
| 6 | 69th | SP Yovani Gallardo Mil |
| 7 | 76th | 1B Mark Reynolds Cle |
| 8 | 93rd | RP Drew Storen Was |
| 9 | 100th | RP Mariano Rivera NYA |
| 10 | 117th | 1B Corey Hart Mil |
| 11 | 124th | RP Joe Nathan Tex |
| 12 | 141st | SP Ervin Santana KC |
| 13 | 148th | OF Colby Rasmus Tor |
| 14 | 165th | SP Jaime Garcia StL |
| 15 | 172nd | 1B Gaby Sanchez Pit |
| 16 | 189th | SP Jair Jurrjens Atl |
| 17 | 196th | SP Ivan Nova NYA |
| 18 | 213th | SP Ricky Nolasco Mia |
| 19 | 220th | SP Edwin Jackson ChN |
| 20 | 237th | OF Peter Bourjos LAA |
| 21 | 244th | SP Gavin Floyd ChA |
| 22 | 261st | SS Jed Lowrie Hou |
| 23 | 268th | 3B Chipper Jones Ret |
| 24 | 285th | 2B Johnny Giavotella KC |
| 25 | 292nd | C John Buck Mia |
| 26 | 309th | OF Mike Carp Sea |
| 27 | 316th | SP Randy Wolf Mil |
| 28 | 333rd | 3B Chris Johnson Ari |
| 29 | 340th | C A.J. Pierzynski Tex |