| Round | Overall | Player |
|---|---|---|
| 1 | 11th | OF Jose Bautista Tor |
| 2 | 14th | 1B Mark Teixeira NYA |
| 3 | 35th | 3B Alex Rodriguez NYA |
| 4 | 38th | SP C.C. Sabathia NYA |
| 5 | 59th | SP James Shields KC |
| 6 | 62nd | SP Stephen Strasburg Was |
| 7 | 83rd | SP Daniel Hudson Ari |
| 8 | 86th | C Matt Wieters Bal |
| 9 | 107th | RP Heath Bell Ari |
| 10 | 110th | DH Billy Butler KC |
| 11 | 131st | OF Delmon Young Det |
| 12 | 134th | OF Yoenis Cespedes Oak |
| 13 | 155th | OF Mike Trout LAA |
| 14 | 158th | RP Ryan Madson Cin |
| 15 | 179th | SP Jhoulys Chacin Col |
| 16 | 182nd | SP Justin Masterson Cle |
| 17 | 203rd | SP Chris Sale ChA |
| 18 | 206th | RP Kyle Farnsworth TB |
| 19 | 227th | 3B Chase Headley SD |
| 20 | 230th | 2B Kelly Johnson Tor |
| 21 | 251st | SS Zach Cozart Cin |
| 22 | 254th | 1B Bryan Lahair ChN |
| 23 | 275th | SP Luke Hochevar KC |
| 24 | 278th | SP Trevor Bauer Cle |
| 25 | 299th | 2B Ryan Raburn Det |
| 26 | 302nd | SP Jarrod Parker Oak |
| 27 | 323rd | C Kurt Suzuki Was |
| 28 | 326th | 2B Alexi Casilla Min |
| 29 | 347th | OF Jose Tabata Pit |