| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | 1B Albert Pujols LAA |
| 2 | 22nd | SS Jose Reyes Tor |
| 3 | 27th | 2B Dustin Pedroia Bos |
| 4 | 46th | OF Matt Holliday StL |
| 5 | 51st | SP Cole Hamels Phi |
| 6 | 70th | SP Adam Wainwright StL |
| 7 | 75th | DH Billy Butler KC |
| 8 | 94th | OF Shin-Soo Choo Tex |
| 9 | 99th | 3B Martin Prado Ari |
| 10 | 118th | OF Josh Reddick Oak |
| 11 | 123rd | SP Doug Fister Was |
| 12 | 142nd | RP Tom Wilhelmsen Sea |
| 13 | 147th | OF Nick Swisher Cle |
| 14 | 166th | SP Jake Peavy Bos |
| 15 | 171st | C Yadier Molina StL |
| 16 | 190th | RP Greg Holland KC |
| 17 | 195th | SP Clay Buchholz Bos |
| 18 | 214th | 3B Kyle Seager Sea |
| 19 | 219th | 1B Chris Carter Hou |
| 20 | 238th | 2B Dustin Ackley Sea |
| 21 | 243rd | SP Andy Pettitte NYA |
| 22 | 262nd | DH Kendrys Morales Sea |
| 23 | 267th | RP Grant Balfour Oak |
| 24 | 286th | SS Jhonny Peralta StL |
| 25 | 291st | SP Shaun Marcum NYN |
| 26 | 310th | OF Ichiro Suzuki NYA |
| 27 | 315th | SP Ivan Nova NYA |
| 28 | 334th | SP Bronson Arroyo Cin |
| 29 | 339th | C John Jaso Oak |