| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Ryan Braun Mil |
| 2 | 23rd | 3B David Wright NYN |
| 3 | 26th | OF Justin Upton Atl |
| 4 | 47th | OF Yoenis Cespedes Oak |
| 5 | 50th | C Carlos Santana Cle |
| 6 | 71st | 2B Brandon Phillips Cin |
| 7 | 74th | 1B Ryan Howard Phi |
| 8 | 95th | SS Ian Desmond Was |
| 9 | 98th | SP Max Scherzer Det |
| 10 | 119th | SP Jon Lester Bos |
| 11 | 122nd | SP Josh Johnson Tor |
| 12 | 143rd | OF Nick Markakis Bal |
| 13 | 146th | RP Mariano Rivera NYA |
| 14 | 167th | RP J.J. Putz Ari |
| 15 | 170th | SP Josh Beckett LAD |
| 16 | 191st | 2B Josh Rutledge Col |
| 17 | 194th | SP A.J. Burnett Pit |
| 18 | 215th | OF Alejandro De Aza ChA |
| 19 | 218th | SP Tom Milone Oak |
| 20 | 239th | SP A.J. Griffin Oak |
| 21 | 242nd | SP Edwin Jackson ChN |
| 22 | 263rd | 1B Justin Smoak Sea |
| 23 | 266th | SS Jean Segura Mil |
| 24 | 287th | OF Brett Gardner NYA |
| 25 | 290th | 1B Mitch Moreland Tex |
| 26 | 311th | C Carlos Ruiz Phi |
| 27 | 314th | SP Chris Tillman Bal |
| 28 | 335th | RP Joaquin Benoit Det |
| 29 | 338th | 3B Lonnie Chisenhall Cle |