| Round | Overall | Player |
|---|---|---|
| 1 | 8th | 1B Joey Votto Cin |
| 2 | 17th | SP Clayton Kershaw LAD |
| 3 | 32nd | OF Jason Heyward Atl |
| 4 | 41st | SP Gio Gonzalez Was |
| 5 | 56th | OF Alex Gordon KC |
| 6 | 65th | SP Chris Sale ChA |
| 7 | 80th | 3B Kevin Youkilis NYA |
| 8 | 89th | SS Elvis Andrus Tex |
| 9 | 104th | C Jesus Montero Sea |
| 10 | 113th | DH Lance Berkman Tex |
| 11 | 128th | SP Alexander Cobb TB |
| 12 | 137th | SP Alexi Ogando Tex |
| 13 | 152nd | RP Fernando Rodney TB |
| 14 | 161st | RP Brandon League LAD |
| 15 | 176th | OF Ichiro Suzuki NYA |
| 16 | 185th | 2B Jose Altuve Hou |
| 17 | 200th | SP Andy Pettitte NYA |
| 18 | 209th | 3B Todd Frazier Cin |
| 19 | 224th | SP Hisashi Iwakuma Sea |
| 20 | 233rd | SP Paul Maholm Atl |
| 21 | 248th | SS Stephen Drew Bos |
| 22 | 257th | OF Colby Rasmus Tor |
| 23 | 272nd | OF Nolan Reimold Bal |
| 24 | 281st | 2B Jurickson Profar Tex |
| 25 | 296th | 2B Gordon Beckham ChA |
| 26 | 305th | SP Henderson Alvarez Mia |
| 27 | 320th | 1B Matt Adams StL |
| 28 | 329th | SP Zack Wheeler NYN |
| 29 | 344th | C Devin Mesoraco Cin |