| Round | Overall | Player |
|---|---|---|
| 1 | 12th | OF Wil Myers TB |
| 2 | 13th | 1B Chris Davis Bal |
| 3 | 36th | SP Felix Hernandez Sea |
| 4 | 37th | 3B Ryan Zimmerman Was |
| 5 | 60th | OF Josh Hamilton LAA |
| 6 | 61st | 2B Ian Kinsler Det |
| 7 | 84th | SS Xander Bogaerts Bos |
| 8 | 85th | SP Johnny Cueto Cin |
| 9 | 108th | SP Jered Weaver LAA |
| 10 | 109th | C Jason Castro Hou |
| 11 | 132nd | SP Clay Buchholz Bos |
| 12 | 133rd | OF Avisail Garcia ChA |
| 13 | 156th | 1B Ryan Howard Phi |
| 14 | 157th | RP Sergio Romo SF |
| 15 | 180th | SP Ervin Santana Atl |
| 16 | 181st | SS J.J. Hardy Bal |
| 17 | 204th | SP Tim Lincecum SF |
| 18 | 205th | 3B Aramis Ramirez Mil |
| 19 | 228th | OF Nate Schierholtz ChN |
| 20 | 229th | SP John Lackey StL |
| 21 | 252nd | 2B Neil Walker Pit |
| 22 | 253rd | C Dioner Navarro Tor |
| 23 | 276th | SP Bronson Arroyo Ari |
| 24 | 277th | OF Andre Ethier LAD |
| 25 | 300th | RP Huston Street LAA |
| 26 | 301st | OF Daniel Nava Bos |
| 27 | 324th | SP Mark Buehrle Tor |
| 28 | 325th | OF Marlon Byrd Phi |
| 29 | 348th | SP Philip Hughes Min |