| Round | Overall | Player |
|---|---|---|
| 1 | 5th | SS Troy Tulowitzki Tor |
| 2 | 20th | 1B Joey Votto Cin |
| 3 | 29th | 1B Chris Davis Bal |
| 4 | 44th | 3B Kris Bryant ChN |
| 5 | 53rd | SP Corey Kluber Cle |
| 6 | 68th | 2B Javier Baez ChN |
| 7 | 77th | OF Jorge Soler ChN |
| 8 | 92nd | SP Gerrit Cole Pit |
| 9 | 101st | OF J.D. Martinez Det |
| 10 | 116th | SP Garrett Richards LAA |
| 11 | 125th | C Matt Wieters Bal |
| 12 | 140th | SP Carlos Carrasco Cle |
| 13 | 149th | SP Jake Arrieta ChN |
| 14 | 164th | OF Joc Pederson LAD |
| 15 | 173rd | SS Jung Ho Kang Pit |
| 16 | 188th | DH Kennys Vargas Min |
| 17 | 197th | SS Marcus Semien Oak |
| 18 | 212th | 1B Mike Napoli Tex |
| 19 | 221st | 3B Trevor Plouffe Min |
| 20 | 236th | SP Nathan Eovaldi NYA |
| 21 | 245th | 3B Miguel Sano Min |
| 22 | 260th | OF Adam Eaton ChA |
| 23 | 269th | C Stephen Vogt Oak |
| 24 | 284th | SP Jimmy Nelson Mil |
| 25 | 293rd | SP C.C. Sabathia NYA |
| 26 | 308th | 3B Joey Gallo Tex |
| 27 | 317th | RP Neftali Feliz Tex |
| 28 | 332nd | 2B Alex Guerrero LAD |
| 29 | 341st | RP Brett Cecil Tor |