| Round | Overall | Player |
|---|---|---|
| 1 | 8th | OF Mookie Betts Bos |
| 2 | 17th | SP Chris Sale Bos |
| 3 | 32nd | OF Ronald Acuna Jr. Atl |
| 4 | 41st | OF Christian Yelich Mil |
| 5 | 56th | OF Byron Buxton Min |
| 6 | 65th | 2B Ozzie Albies Atl |
| 7 | 80th | SS Jean Segura Phi |
| 8 | 89th | SP Chris Archer Pit |
| 9 | 104th | 3B Kyle Seager Sea |
| 10 | 113th | 1B Ryan Zimmerman Was |
| 11 | 128th | SP Trevor Bauer Cle |
| 12 | 137th | OF Eloy Jimenez ChA |
| 13 | 152nd | 3B Maikel Franco Phi |
| 14 | 161st | SP Kevin Gausman Atl |
| 15 | 176th | SP Cole Hamels ChN |
| 16 | 185th | SP Blake Snell TB |
| 17 | 200th | OF Carlos Gonzalez Col |
| 18 | 209th | C Salvador Perez KC |
| 19 | 224th | C Yasmani Grandal LAD |
| 20 | 233rd | OF Victor Robles Was |
| 21 | 248th | SP Dinelson Lamet SD |
| 22 | 257th | SS Andrelton Simmons LAA |
| 23 | 272nd | 2B Jonathan Villar Bal |
| 24 | 281st | OF Stephen Piscotty Oak |
| 25 | 296th | SP Jeff Samardzija SF |
| 26 | 305th | SP Jordan Zimmermann Det |
| 27 | 320th | 1B C.J. Cron TB |
| 28 | 329th | SP Michael Kopech ChA |
| 29 | 344th | OF Delino DeShields Jr. Tex |