| Round | Overall | Player |
|---|---|---|
| 1 | 10th | SP Max Scherzer Was |
| 2 | 15th | OF Giancarlo Stanton NYA |
| 3 | 34th | SP Trevor Bauer Cin |
| 4 | 39th | OF Joey Gallo Tex |
| 5 | 58th | 1B Matt Olson Oak |
| 6 | 63rd | 3B Vladimir Guerrero Jr. Tor |
| 7 | 82nd | OF Eloy Jimenez ChA |
| 8 | 87th | SP Germán Márquez Col |
| 9 | 106th | SS Paul DeJong StL |
| 10 | 111th | 3B Travis Shaw Mil |
| 11 | 130th | RP Kirby Yates SD |
| 12 | 135th | 1B Pete Alonso NYN |
| 13 | 154th | OF Stephen Piscotty Oak |
| 14 | 159th | OF Jesse Winker Cin |
| 15 | 178th | SP Hyun-Jin Ryu LAD |
| 16 | 183rd | SS Elvis Andrus Tex |
| 17 | 202nd | OF Tyler O'Neill StL |
| 18 | 207th | RP Jordan Hicks StL |
| 19 | 226th | SS Jorge Polanco Min |
| 20 | 231st | 2B Garrett Hampson Col |
| 21 | 250th | SP Tyler Skaggs Ret |
| 22 | 255th | DH Tyler White Hou |
| 23 | 274th | C Wellington Castillo ChA |
| 24 | 279th | 3B Johan Camargo Atl |
| 25 | 298th | RP Will Smith SF |
| 26 | 303rd | SP Michael Pineda Min |
| 27 | 322nd | RP Matthew Strahm SD |
| 28 | 327th | C Tom Murphy Sea |
| 29 | 346th | 2B Jeff McNeil NYN |