| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Mookie Betts Bos |
| 2 | 23rd | OF Andrew Benintendi Bos |
| 3 | 26th | SP Justin Verlander Hou |
| 4 | 47th | DH Khris Davis Oak |
| 5 | 50th | SP Clayton Kershaw LAD |
| 6 | 71st | 3B Josh Donaldson Atl |
| 7 | 74th | 2B Scooter Gennett SF |
| 8 | 95th | RP Blake Treinen Oak |
| 9 | 98th | SP Masahiro Tanaka NYA |
| 10 | 119th | OF A.J. Pollock LAD |
| 11 | 122nd | 1B Miguel Cabrera Det |
| 12 | 143rd | RP David Robertson Phi |
| 13 | 146th | SP Shane Bieber Cle |
| 14 | 167th | SS Didi Gregorius NYA |
| 15 | 170th | SP Eduardo Rodriguez Bos |
| 16 | 191st | 1B Yulieski Gurriel Hou |
| 17 | 194th | SP Andrew Heaney LAA |
| 18 | 215th | C Robinson Chirinos Hou |
| 19 | 218th | SS Amed Rosario NYN |
| 20 | 239th | 3B Jonathan Villar Mia |
| 21 | 242nd | 3B Matt Davidson Tex |
| 22 | 263rd | SS Troy Tulowitzki NYA |
| 23 | 266th | SP Dereck Rodríguez SF |
| 24 | 287th | SP Jimmy Nelson Mil |
| 25 | 290th | OF Ender Inciarte Atl |
| 26 | 311th | 1B Ronald Guzman Tex |
| 27 | 314th | SP Zach Eflin Phi |
| 28 | 335th | C Mitch Garver Min |
| 29 | 338th | 1B José Martínez StL |