| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Mookie Betts Bos |
| 2 | 23rd | SP Justin Verlander Hou |
| 3 | 26th | 3B Kris Bryant ChN |
| 4 | 47th | OF Cody Bellinger LAD |
| 5 | 50th | SP Jack Flaherty StL |
| 6 | 71st | OF David Dahl Col |
| 7 | 74th | SP Jose Berrios Min |
| 8 | 95th | SS Adalberto Mondesí KC |
| 9 | 98th | 2B Rougned Odor Tex |
| 10 | 119th | SP Shane Bieber Cle |
| 11 | 122nd | 1B Miguel Cabrera Det |
| 12 | 143rd | OF Andrew McCutchen Phi |
| 13 | 146th | C Yadier Molina StL |
| 14 | 167th | SP Jose Quintana ChN |
| 15 | 170th | RP Ken Giles Tor |
| 16 | 191st | DH Shohei Ohtani LAA |
| 17 | 194th | SS Elvis Andrus Tex |
| 18 | 215th | 3B Jeimer Candelario Det |
| 19 | 218th | C Wellington Castillo ChA |
| 20 | 239th | SP Nick Pivetta Phi |
| 21 | 242nd | 1B Justin Bour LAA |
| 22 | 263rd | RP Alex Colome ChA |
| 23 | 266th | SP Luke Weaver Ari |
| 24 | 287th | 2B Jeff McNeil NYN |
| 25 | 290th | SP Alex Wood Cin |
| 26 | 311th | OF Ian Happ ChN |
| 27 | 314th | RP Andrew Miller StL |
| 28 | 335th | SP Touki Toussaint Atl |
| 29 | 338th | OF Kole Calhoun LAA |