| Round | Overall | Player |
|---|---|---|
| 1 | 4th | 3B Nolan Arenado Col |
| 2 | 21st | 1B Rhys Hoskins Phi |
| 3 | 28th | OF Andrew Benintendi Bos |
| 4 | 45th | SP Carlos Carrasco Cle |
| 5 | 52nd | SS Gleyber Torres NYA |
| 6 | 69th | OF Nick Castellanos ChN |
| 7 | 76th | SP David Price Bos |
| 8 | 93rd | 1B Pete Alonso NYN |
| 9 | 100th | RP Wade Davis Col |
| 10 | 117th | RP Kirby Yates SD |
| 11 | 124th | 3B Rafael Devers Bos |
| 12 | 141st | SP J.A. Happ NYA |
| 13 | 148th | OF Byron Buxton Min |
| 14 | 165th | SS Elvis Andrus Tex |
| 15 | 172nd | SP Luis Castillo Cin |
| 16 | 189th | C Francisco Mejia SD |
| 17 | 196th | SS Willy Adames TB |
| 18 | 213th | SP Zack Godley Ari |
| 19 | 220th | 1B Brandon Belt SF |
| 20 | 237th | OF Marwin Gonzalez Min |
| 21 | 244th | OF Avisail Garcia TB |
| 22 | 261st | SP Kevin Gausman Atl |
| 23 | 268th | RP José Alvarado TB |
| 24 | 285th | RP Dakota Hudson StL |
| 25 | 292nd | 2B Ian Kinsler SD |
| 26 | 309th | SP Mike Minor Tex |
| 27 | 316th | OF Teoscar Hernández Tor |
| 28 | 333rd | C John Hicks Det |
| 29 | 340th | SP Alex Reyes StL |