| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Mookie Betts Bos |
| 2 | 23rd | SS Trevor Story Col |
| 3 | 26th | SP Jacob deGrom NYN |
| 4 | 47th | SP Walker Buehler LAD |
| 5 | 50th | OF Joey Gallo Tex |
| 6 | 71st | 1B Miguel Cabrera Det |
| 7 | 74th | OF David Dahl Col |
| 8 | 95th | 3B Yoan Moncada ChA |
| 9 | 98th | SP Germán Márquez Col |
| 10 | 119th | 3B Josh Donaldson Atl |
| 11 | 122nd | OF Max Kepler Min |
| 12 | 143rd | SP Joe Musgrove Pit |
| 13 | 146th | OF Nick Senzel Cin |
| 14 | 167th | RP Jordan Hicks StL |
| 15 | 170th | 1B Matt Olson Oak |
| 16 | 191st | OF Jesse Winker Cin |
| 17 | 194th | SS Jorge Polanco Min |
| 18 | 215th | 3B Miguel Sano Min |
| 19 | 218th | OF Ryan Braun Mil |
| 20 | 239th | RP Will Smith SF |
| 21 | 242nd | C Wellington Castillo ChA |
| 22 | 263rd | 2B Brandon Lowe TB |
| 23 | 266th | RP Pedro Strop ChN |
| 24 | 287th | 3B Johan Camargo Atl |
| 25 | 290th | SP Corbin Burnes Mil |
| 26 | 311th | SP Brandon Woodruff Mil |
| 27 | 314th | C Austin Hedges SD |
| 28 | 335th | 1B Eric Thames Mil |
| 29 | 338th | RP Sergio Romo Min |