| Round | Overall | Player |
|---|---|---|
| 1 | 11th | 3B Nolan Arenado Col |
| 2 | 14th | SP Gerrit Cole NYA |
| 3 | 35th | 1B Anthony Rizzo ChN |
| 4 | 38th | SS Javier Baez ChN |
| 5 | 59th | OF Aaron Judge NYA |
| 6 | 62nd | SP Aaron Nola Phi |
| 7 | 83rd | RP Kirby Yates SD |
| 8 | 86th | RP Roberto Osuna Hou |
| 9 | 107th | OF Ramón Laureano Oak |
| 10 | 110th | OF Luis Robert ChA |
| 11 | 131st | OF Whit Merrifield KC |
| 12 | 134th | C Will Smith LAD |
| 13 | 155th | 2B Gavin Lux LAD |
| 14 | 158th | SP Germán Márquez Col |
| 15 | 179th | SP Michael Fiers Oak |
| 16 | 182nd | 1B Yulieski Gurriel Hou |
| 17 | 203rd | 3B Scott Kingery Phi |
| 18 | 206th | SP Justus Sheffield Sea |
| 19 | 227th | OF Danny Santana Tex |
| 20 | 230th | SP J.A. Happ NYA |
| 21 | 251st | C Wilson Ramos NYN |
| 22 | 254th | SP Michael Kopech ChA |
| 23 | 275th | DH Renato Núñez Bal |
| 24 | 278th | 2B Jonathan Schoop Det |
| 25 | 299th | SP Reynaldo Lopez ChA |
| 26 | 302nd | 3B Todd Frazier Tex |
| 27 | 323rd | OF David Peralta Ari |
| 28 | 326th | 1B Dan Murphy Col |
| 29 | 347th | SS Nick Ahmed Ari |