| Round | Overall | Player |
|---|---|---|
| 1 | 6th | OF Mookie Betts LAD |
| 2 | 19th | SS Trevor Story Col |
| 3 | 30th | 3B Vladimir Guerrero Jr Tor |
| 4 | 43rd | SP Luis Castillo Cin |
| 5 | 54th | 1B Joshua Bell Was |
| 6 | 67th | SP Chris Paddack SD |
| 7 | 78th | SS Carlos Correa Hou |
| 8 | 91st | OF Andrew Benintendi Bos |
| 9 | 102nd | SP Trevor Bauer Cin |
| 10 | 115th | OF David Dahl Tex |
| 11 | 126th | SP Hyun-Jin Ryu Tor |
| 12 | 139th | 3B Jeff McNeil NYN |
| 13 | 150th | 2B Jean Segura Phi |
| 14 | 163rd | SP Dallas Keuchel ChA |
| 15 | 174th | 1B Luke Voit NYA |
| 16 | 187th | SP Robbie Ray Tor |
| 17 | 198th | SP Sandy Alcántra Mia |
| 18 | 211th | OF Bryan Reynolds Pit |
| 19 | 222nd | SP Luke Weaver Ari |
| 20 | 235th | C Danny Jansen Tor |
| 21 | 246th | SS Elvis Andrus Tex |
| 22 | 259th | C Jorge Alfaro Mia |
| 23 | 270th | 2B Nico Hoerner ChN |
| 24 | 283rd | OF Shogo Akiyama Cin |
| 25 | 294th | SP Adrian Houser Mil |
| 26 | 307th | SP Dylan Cease ChA |
| 27 | 318th | OF Anthony Santander Bal |
| 28 | 331st | OF Dylan Carlson StL |
| 29 | 342nd | SP Zach Eflin Phi |