| Round | Overall | Player |
|---|---|---|
| 1 | 5th | OF Juan Soto Was |
| 2 | 20th | SS Trevor Story Col |
| 3 | 29th | 3B Jose Ramirez Cle |
| 4 | 44th | OF Eloy Jimenez ChA |
| 5 | 53rd | SS Fernando Tatis Jr. SD |
| 6 | 68th | 1B Joshua Bell Was |
| 7 | 77th | SP Jose Berrios Min |
| 8 | 92nd | SP Mike Soroka Atl |
| 9 | 101st | 2B Gavin Lux LAD |
| 10 | 116th | SP Zach Wheeler Phi |
| 11 | 125th | C Will Smith LAD |
| 12 | 140th | SP James Paxton NYA |
| 13 | 149th | RP Raisel Iglesias LAA |
| 14 | 164th | RP Hansel Robles Min |
| 15 | 173rd | 2B Brandon Lowe TB |
| 16 | 188th | SP Kenta Maeda Min |
| 17 | 197th | 3B Austin Riley Atl |
| 18 | 212th | OF Sam Hilliard Col |
| 19 | 221st | OF Kole Calhoun Ari |
| 20 | 236th | OF Yoshitomo Tsutsugo TB |
| 21 | 245th | SP Joey Lucchesi SD |
| 22 | 260th | 1B Justin Smoak Ret |
| 23 | 269th | SS Nick Ahmed Ari |
| 24 | 284th | C Francisco Mejia SD |
| 25 | 293rd | OF Dylan Carlson StL |
| 26 | 308th | SP Yusei Kikuchi Sea |
| 27 | 317th | 3B Carter Kieboom Was |
| 28 | 332nd | RP Keone Kela Pit |
| 29 | 341st | SP Zach Eflin Phi |