| Round | Overall | Player |
|---|---|---|
| 1 | 10th | 3B Nolan Arenado Col |
| 2 | 15th | SP Jacob deGrom NYN |
| 3 | 34th | SP Clayton Kershaw LAD |
| 4 | 39th | 3B Vladimir Guerrero Jr Tor |
| 5 | 58th | SS Bo Bichette Tor |
| 6 | 63rd | 1B Miguel Sano Min |
| 7 | 82nd | SP Noah Syndergaard NYN |
| 8 | 87th | SP Jesus Luzardo Oak |
| 9 | 106th | SP Tyler Glasnow TB |
| 10 | 111th | SP Julio Urías LAD |
| 11 | 130th | OF Kyle Schwarber ChN |
| 12 | 135th | 2B Ryan McMahon Col |
| 13 | 154th | SP Aaron Civale Cle |
| 14 | 159th | OF Ramón Laureano Oak |
| 15 | 178th | OF Willie Calhoun Tex |
| 16 | 183rd | 2B Michael Chavis Bos |
| 17 | 202nd | OF Nick Senzel Cin |
| 18 | 207th | OF David Peralta Ari |
| 19 | 226th | 3B Yandy Diaz TB |
| 20 | 231st | 1B Ryan O'Hearn KC |
| 21 | 250th | SP Johnny Cueto SF |
| 22 | 255th | SS Elvis Andrus Tex |
| 23 | 274th | OF Austin Hays Bal |
| 24 | 279th | OF Brett Gardner NYA |
| 25 | 298th | SP Adrian Houser Mil |
| 26 | 303rd | C Austin Nola SD |
| 27 | 322nd | SP Mitch Keller Pit |
| 28 | 327th | C Jason Castro SD |
| 29 | 346th | OF A.J. Pollock LAD |