| Round | Overall | Player |
|---|---|---|
| 1 | 12th | SP Walker Buehler LAD |
| 2 | 13th | SP Jacob deGrom NYN |
| 3 | 36th | 3B Vladimir Guerrero Jr Tor |
| 4 | 37th | 2B Ozzie Albies Atl |
| 5 | 60th | SS Xander Bogaerts Bos |
| 6 | 61st | 1B Miguel Sano Min |
| 7 | 84th | RP Aroldis Chapman NYA |
| 8 | 85th | RP Roberto Osuna Hou |
| 9 | 108th | SP Jesus Luzardo Oak |
| 10 | 109th | DH Edwin Encarnacion ChA |
| 11 | 132nd | SP Kyle Hendricks ChN |
| 12 | 133rd | OF Lourdes Gurriel Tor |
| 13 | 156th | 3B Miguel Andújar NYA |
| 14 | 157th | RP Craig Kimbrel ChN |
| 15 | 180th | OF Willie Calhoun Tex |
| 16 | 181st | SS Jorge Polanco Min |
| 17 | 204th | OF Nomar Mazara ChA |
| 18 | 205th | 2B Brandon Lowe TB |
| 19 | 228th | OF Mitch Haniger Sea |
| 20 | 229th | SP Adrian Houser Mil |
| 21 | 252nd | OF Sam Hilliard Col |
| 22 | 253rd | SP Steven Matz NYN |
| 23 | 276th | 1B Justin Smoak Ret |
| 24 | 277th | C Danny Jansen Tor |
| 25 | 300th | OF Oscar Mercado Cle |
| 26 | 301st | OF Dylan Carlson StL |
| 27 | 324th | SP Yonny Chirinos TB |
| 28 | 325th | DH Renato Núñez Bal |
| 29 | 348th | C Jason Castro SD |