| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Ronald Acuna Jr. Atl |
| 2 | 23rd | OF Aaron Judge NYA |
| 3 | 26th | OF George Springer Hou |
| 4 | 47th | 1B Jose Abreu ChA |
| 5 | 50th | 3B Kris Bryant ChN |
| 6 | 71st | SS Bo Bichette Tor |
| 7 | 74th | SP Lucas Giolito ChA |
| 8 | 95th | SP Tyler Glasnow TB |
| 9 | 98th | 2B Ryan McMahon Col |
| 10 | 119th | RP Kenley Jansen LAD |
| 11 | 122nd | SP James Paxton NYA |
| 12 | 143rd | 1B Christian Walker Ari |
| 13 | 146th | RP Brandon Workman Bos |
| 14 | 167th | RP Mark Melancon Atl |
| 15 | 170th | C Wilson Ramos NYN |
| 16 | 191st | SP Dylan Bundy LAA |
| 17 | 194th | 1B Eric Hosmer SD |
| 18 | 215th | OF David Peralta Ari |
| 19 | 218th | 3B Justin Turner LAD |
| 20 | 239th | SP Zach Eflin Phi |
| 21 | 242nd | SS Kevin Newman Pit |
| 22 | 263rd | OF Corey Dickerson Mia |
| 23 | 266th | C Yadier Molina StL |
| 24 | 287th | SP Miles Mikolas StL |
| 25 | 290th | 2B Dee Strange-Gordon Sea |
| 26 | 311th | SP Zach Davies SD |
| 27 | 314th | OF Mike Yastrzemski SF |
| 28 | 335th | SP Josh James Hou |
| 29 | 338th | SP Anibal Sanchez Was |